SPR microscopy integrates optical microscopy and SPR into one system.  It provides high-quality data on kinetics and affinity of cell membrane proteins and spatial visualization of cellular structures. Real-time interactions of the drug and membrane protein can be measured in its native state without needing to extract proteins from the cell. Because of its unique measurement of cell membrane proteins on the cell, SPRM has become a powerful tool that provide information about various drug compounds and drug affinity. Antibody-interaction studies are also used to investigate disease pathways and targets for potential drug therapies, and much more.

The system measures nanometer scale binding activities needed for the study of bacteria and virus interactions and the development of new methods for nanoparticle drug delivery.