Applications of Cell-based SPR Microscopy with AstraZeneca

Speakers:
Dr. Niklas Larsson, Associate Prinicipal Scientist, AstraZeneca
Dr. Shijie Wu, Applications Scientist, Biosensing Instrument

Key learnings:
– Understand principles of SPR microscopy.
– See small molecule and antibody binding case studies
– Learn about receptor pharmacology studies on GPR39 via cellular assay
– Demonstrate target engagement for membrane receptors including presentation of GPR39 SPRM data.

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Cell-based Label-free Binding Affinity and Kinetics Using SPR Microscopy Technology

Speakers: 
Late Prof Nongjian “NJ” Tao, PhD, Center Director and Professor, Biodesign Center for Bioelectronics and Biosensors, Arizona State University
Dr. Shijie Wu, Applications Scientist, Biosensing Instrument

Key learnings:
– Understand principles of SPR microscopy.
– See application examples developed with Pfizer, AstraZeneca, and others.
– Explore SPRM studies of HER2 (human epidermal growth factor receptor 2) and Herceptin interactions.
– Discuss detection of single exosomes using an enhanced SPR microscope set up.

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表面等离子体基元共振细胞分析仪: 原理与应用

报告人:武仕杰, Applications Scientist, Biosensing Instrument
专门针对细胞表面膜蛋白及相关分子无标记检测而设计的SPRM 200, 使您在不需要提取分离膜蛋白的前提下实时观测细胞状态并同时测量药物分子与靶点在细胞上的动力学结合过程。

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Introduction of Electrochemistry SPR

Speakers:
Dr. Shijie Wu, Applications Scientist, Biosensing Instrument

Key learnings:
– Basic of EC SPR
– Application examples of EC-SPR and EC-DualFlow Analysis modules

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